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CS-W001157 4
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2,3,4,9-Tetrahydro-1H-carbazol-3-ol

  • CAS No. 14384-34-0

  • Cat. No. CS-0097435
  • Purity≥97%
  • MDL No.MFCD01924666

*For research and further manufacturing use only, not for direct human use.

2,3,4,9-Tetrahydro-1H-carbazol-3-ol|CS-0097435

Structure of 14384-34-0

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General Information

  • CAS No. 14384-34-0
  • Cat. No. CS-0097435
  • Purity ≥97%
  • MDL No. MFCD01924666
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃NO
  • Molecular Weight 187.24
  • Synonym(s) 3-hydroxy-1,2,3,4-tetrahydrocarbazole
  • SMILES OC1CCC2=C(C1)C(C=CC=C3)=C3N2

Description

This tetrahydrocarbazol-3-ol derivative features a stable, electron-rich carbazole core with a hydroxyl group at the 3-position, enabling direct functionalization in synthetic routes. The saturated ring system enhances solubility and handling compared to fully aromatic analogs, while the phenolic OH supports hydrogen bonding in catalytic or supramolecular applications.

Application

2,3,4,9-Tetrahydro-1H-carbazol-3-ol serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its phenolic hydroxyl group enables direct derivatization, while the saturated carbazole core offers enhanced metabolic stability and π-conjugation potential. The compound exhibits good bench stability and facilitates efficient functionalization in standard coupling and oxidation protocols, making it valuable for scaffold diversification in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   36.02
  • LogP   2.0175
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

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