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Structure of 1434631-44-3
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2-Amino-3-bromo-5-(trifluoromethyl)benzoic acid features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the bromo substituent enables facile cross-coupling. The amino and carboxylic acid functionalities provide versatile handles for peptide conjugation and salt formation, making this compound suitable for bioactive molecule synthesis under standard conditions.
2-Amino-3-bromo-5-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via palladium-catalyzed coupling reactions. Its ortho-bromine and carboxylic acid groups provide complementary handles for C–C and C–N bond formation, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The molecule exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: