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CS-W001157 4
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Azido-PEG5-NHS ester

  • CAS No. 1433996-86-1

  • Cat. No. CS-0114773
  • Molecule weight432.43
  • Purity≥98%
  • MDL No.MFCD24539474

*For research and further manufacturing use only, not for direct human use.

Azido-PEG5-NHS ester|CS-0114773

Structure of 1433996-86-1

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General Information

  • CAS No. 1433996-86-1
  • Cat. No. CS-0114773
  • Purity ≥98%
  • MDL No. MFCD24539474
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈N₄O₉
  • Molecular Weight 432.43
  • Synonym(s) None
  • SMILES O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]

Description

Azido-PEG5-NHS ester features a cleavable NHS ester for amine conjugation and a terminal azide group enabling bioorthogonal click chemistry. This bifunctional linker integrates seamlessly into protein labeling, probe synthesis, and surface immobilization workflows under standard conditions.

Application

Azido-PEG5-NHS ester serves as a versatile bifunctional linker for bioconjugation, enabling efficient coupling of azide-containing molecules to primary amines under mild conditions. The PEG5 spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester offers high reactivity toward amine groups. This reagent facilitates site-specific labeling in peptide, protein, and oligonucleotide modifications, with excellent stability during storage and straightforward purification via standard protocols.

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   158.59
  • LogP   0.377
  • H_Acceptors   10
  • H_Donors   0
  • Rotatable_Bonds   19

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