Azido-PEG5-NHS ester

Name: Azido-PEG5-NHS ester
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1433996-86-1
Cat. No. CS-0114773
Purity≥98%
MDL No.MFCD24539474

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Azido-PEG5-NHS ester features a cleavable NHS ester for amine conjugation and a terminal azide group enabling bioorthogonal click chemistry. This bifunctional linker integrates seamlessly into protein labeling, probe synthesis, and surface immobilization workflows under standard conditions.

Application

Azido-PEG5-NHS ester serves as a versatile bifunctional linker for bioconjugation, enabling efficient coupling of azide-containing molecules to primary amines under mild conditions. The PEG5 spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester offers high reactivity toward amine groups. This reagent facilitates site-specific labeling in peptide, protein, and oligonucleotide modifications, with excellent stability during storage and straightforward purification via standard protocols.

General Information

CAS No. 1433996-86-1
Cat. No. CS-0114773
Purity ≥98%
MDL No. MFCD24539474
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₇H₂₈N₄O₉
Molecular Weight 432.43
Synonym(s) None
SMILES O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]

Computational Chemistry Data

TPSA 158.59
LogP 0.377
H_Acceptors 10
H_Donors 0
Rotatable_Bonds 19

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Functional Group PEG

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Life Science Linker PEG Azide

Life Science Linker PEG NHS ester

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

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Azido-PEG5-NHS ester

CAS No. 1433996-86-1

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