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Structure of 143328-21-6
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This cyclopentane carboxylic acid derivative features a 3-chlorophenyl group directly attached to the cyclopentane ring, delivering enhanced lipophilicity and metabolic stability. The electron-withdrawing chlorine substituent modulates reactivity and influences binding affinity in target-directed synthesis. Ideal for medicinal chemistry applications requiring rigid, aromatic-aliphatic scaffolds with tunable physicochemical properties.
1-(3-Chlorophenyl)cyclopentane-1-carboxylic acid serves as a versatile building block for medicinal chemistry campaigns, enabling the construction of bioactive scaffolds through standard functional group transformations. Its cyclopentane core provides conformational rigidity, while the 3-chlorophenyl moiety offers enhanced lipophilicity and potential for π–π interactions. The carboxylic acid functionality facilitates derivatization via amide coupling, esterification, or salt formation, supporting downstream synthetic pathways in API development. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: