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CS-W001157 4
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(R)-1-(2-nitrophenyl)ethanamine hydrochloride

  • CAS No. 1431699-56-7

  • Cat. No. CS-B0173
  • Purity≥96%
  • MDL No.MFCD24411694

*For research and further manufacturing use only, not for direct human use.

(R)-1-(2-nitrophenyl)ethanamine hydrochloride|CS-B0173

Structure of 1431699-56-7

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General Information

  • CAS No. 1431699-56-7
  • Cat. No. CS-B0173
  • Purity ≥96%
  • MDL No. MFCD24411694
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁ClN₂O₂
  • Molecular Weight 202.64
  • Synonym(s) (R)-2-Nitro-α-methylbenzylamine Hydrochloride
  • SMILES C[C@@H](N)C1=CC=CC=C1[N+]([O-])=O.[H]Cl

Description

(R)-1-(2-nitrophenyl)ethanamine hydrochloride is a chiral amine featuring a para-nitro group on a phenyl ring, offering high enantiomeric purity and enhanced solubility in aqueous and polar organic media. This bench-stable derivative serves as a key building block in asymmetric synthesis, enabling efficient access to nitrogen-containing pharmaceutical intermediates through stereoselective coupling reactions.

Application

(R)-1-(2-Nitrophenyl)ethanamine hydrochloride serves as a chiral building block for asymmetric synthesis, enabling efficient access to enantiomerically pure β-aminocarboxylic acid derivatives and nitrogen-containing heterocycles. Its bench-stable hydrochloride salt facilitates handling and purification, while the ortho-nitro group supports directed metallation and subsequent functionalization in multi-step sequences. Functions reliably in standard amine coupling and reduction protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.16
  • LogP   2.0363
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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