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Structure of 142994-05-6
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This methylthio-trifluoromethyl-substituted benzoic acid features a sterically unhindered carboxylate group flanked by electron-deficient aryl substituents, enabling direct functionalization in cross-coupling and amidation protocols under standard conditions.
2-(Methylthio)-4-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical scaffolds. Its orthogonal functional groups—carboxylic acid and methylthio—facilitate selective derivatization, while the electron-withdrawing trifluoromethyl group enhances metabolic stability. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient access to diverse analogs in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: