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CS-W001157 4
Total: USD 88.00

(R)-2-(4-nitrophenyl)propanoic acid

  • CAS No. 142927-07-9

  • Cat. No. CS-0569112
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-2-(4-nitrophenyl)propanoic acid|CS-0569112

Structure of 142927-07-9

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General Information

  • CAS No. 142927-07-9
  • Cat. No. CS-0569112
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₄
  • Molecular Weight 195.17
  • Synonym(s) None
  • SMILES C[C@H](C1=CC=C(C=C1)[N+](=O)[O-])C(=O)O

Description

(R)-2-(4-Nitrophenyl)propanoic acid is a chiral carboxylic acid featuring a para-nitro aryl group and a stereogenic center. This configuration imparts distinct reactivity and binding properties, making it valuable for asymmetric synthesis and the development of enantioselective pharmaceutical intermediates. The molecule exhibits enhanced stability under standard bench conditions.

Application

(R)-2-(4-Nitrophenyl)propanoic acid serves as a valuable chiral building block for synthesizing pharmaceutically relevant scaffolds. Its well-defined stereochemistry and stable nitroaryl functionality enable reliable transformations in asymmetric synthesis, including decarboxylation, reduction to the corresponding amine, or coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for use in medicinal chemistry campaigns and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   80.44
  • LogP   1.7829
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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