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CS-W001157 4
Total: USD 88.00

(E)-3-(4-Fluorophenyl)acrylic acid

  • CAS No. 14290-86-9

  • Cat. No. CS-0077011
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-3-(4-Fluorophenyl)acrylic acid|CS-0077011

Structure of 14290-86-9

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General Information

  • CAS No. 14290-86-9
  • Cat. No. CS-0077011
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇FO₂
  • Molecular Weight 166.15
  • Synonym(s) 4-Fluorocinnamic acid
  • SMILES O=C(O)/C=C/C1=CC=C(F)C=C1

Description

(E)-3-(4-Fluorophenyl)acrylic acid is a bench-stable, electron-deficient α,β-unsaturated carboxylic acid featuring a para-fluorinated aryl group. This structural motif enables direct incorporation into Michael acceptor systems and facilitates conjugated extension in synthetic routes to bioactive molecules and functional materials.

Application

(E)-3-(4-Fluorophenyl)acrylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of conjugated systems and heterocyclic scaffolds. Its well-defined stereochemistry and stability under standard reaction conditions facilitate reliable coupling and functionalization. The molecule functions effectively in Heck, Suzuki, and Michael addition reactions, offering predictable reactivity for drug discovery applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.9235
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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