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Sodium m-hydroxybenzenesulfonate

  • CAS No. 14278-60-5

  • Cat. No. CS-0138195
  • Molecule weight196.16
  • Purity≥95%
  • MDL No.MFCD00464504

*For research and further manufacturing use only, not for direct human use.

Sodium m-hydroxybenzenesulfonate|CS-0138195

Structure of 14278-60-5

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General Information

  • CAS No. 14278-60-5
  • Cat. No. CS-0138195
  • Purity ≥95%
  • MDL No. MFCD00464504
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅NaO₄S
  • Molecular Weight 196.16
  • Synonym(s) Sodium 3-hydroxybenzenesulfonate
  • SMILES [Na].O=S(=O)(O)C=1C=CC=C(O)C1

Description

Sodium m-hydroxybenzenesulfonate features a meta-hydroxyl group flanking a sulfonate moiety on the benzene ring, delivering enhanced water solubility and stability under physiological conditions. This combination enables reliable use in aqueous reaction media, particularly in synthetic routes requiring pH-controlled environments or as a functionalized building block in dye and pharmaceutical intermediates.

Application

Sodium m-hydroxybenzenesulfonate serves as a stable, water-soluble platform for ortho-directed electrophilic substitution and sulfonation reactions. Its phenolic hydroxyl and meta-sulfonate groups enable predictable regioselectivity in aromatic functionalization, facilitating the synthesis of complex heterocycles and intermediates for pharmaceutical and agrochemical applications. The compound exhibits excellent bench stability and simplifies purification in aqueous workups.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   0.2581
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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