7-Bromoimidazo[1,2-a]pyridin-3-amine

Name: 7-Bromoimidazo[1,2-a]pyridin-3-amine
Brand: ChemScene
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CAS No. 1427439-69-7
Cat. No. CS-0214447
Purity≥96%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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7-Bromoimidazo[1,2-a]pyridin-3-amine|CS-0214447

Structure of 1427439-69-7

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General Information

CAS No. 1427439-69-7
Cat. No. CS-0214447
Purity ≥96%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrN₃
Molecular Weight 212.05
Synonym(s) None
SMILES NC1=CN=C2C=C(Br)C=CN21

Description

7-Bromoimidazo[1,2-a]pyridin-3-amine serves as a versatile heterocyclic scaffold for medicinal chemistry and catalysis. The bromo substituent enables palladium-catalyzed cross-coupling reactions, while the imidazopyridine core offers enhanced metabolic stability and favorable binding interactions in kinase-targeted drug discovery.

Application

7-Bromoimidazo[1,2-a]pyridin-3-amine serves as a versatile building block for medicinal chemistry and catalytic cross-coupling applications. The bromo group enables palladium-catalyzed transformations such as Suzuki-Miyaura and Buchwald-Hartwig couplings, while the imidazo[1,2-a]pyridine core provides a rigid, electron-deficient heterocyclic scaffold with favorable pharmacokinetic properties. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to complex nitrogen-containing architectures in drug discovery campaigns.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 43.32
LogP 1.679
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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7-Bromoimidazo[1,2-a]pyridin-3-amine

CAS No. 1427439-69-7

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