6-Bromo-4-fluoro-2-methylbenzo[d]thiazole

Name: 6-Bromo-4-fluoro-2-methylbenzo[d]thiazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1427433-65-5
Cat. No. CS-0527235
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-4-fluoro-2-methylbenzo[d]thiazole|CS-0527235

Structure of 1427433-65-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Bromo-4-fluoro-2-methylbenzo[d]thiazole features a fused heterocyclic core with strategically positioned halogen and methyl substituents. This electron-deficient scaffold enables efficient coupling in cross-coupling reactions, particularly Pd-catalyzed variants. The bromine atom serves as a high-reactivity handle for C–C bond formation, while the fluorine enhances metabolic stability and modulates electronic properties. Bench-stable under standard conditions, it integrates readily into complex molecular architectures.

Application

6-Bromo-4-fluoro-2-methylbenzo[d]thiazole serves as a versatile building block in the synthesis of biologically active heterocycles and pharmaceutical intermediates. Its orthogonal halogenation pattern enables selective cross-coupling reactions, while the methyl group provides a handle for further functionalization. The molecule exhibits excellent bench stability and compatibility with palladium-catalyzed transformations, facilitating efficient access to complex scaffolds in medicinal chemistry and process development workflows.

General Information

CAS No. 1427433-65-5
Cat. No. CS-0527235
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅BrFNS
Molecular Weight 246.10
Synonym(s) 6-Bromo-4-fluoro-2-methyl-1,3-benzothiazole
SMILES CC1=NC2=C(F)C=C(Br)C=C2S1

Computational Chemistry Data

TPSA 12.89
LogP 3.50632
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Benzothiazole compounds

Key Words

1427433-65-5 sigma1427433-65-5 manufacturer1427433-65-5 price1427433-65-5 structure1427433-65-5 SDSbuy 1427433-65-51427433-65-5 supplier1427433-65-5 uses1427433-65-5 molecular weightprice of 1427433-65-51427433-65-5 chemical name formula of 1427433-65-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Bromo-4-fluoro-2-methylbenzo[d]thiazole

CAS No. 1427433-65-5

Recommended Products