6-Bromo-7-methylpyrazolo[1,5-a]pyridine

Name: 6-Bromo-7-methylpyrazolo[1,5-a]pyridine
Brand: ChemScene
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CAS No. 1427382-24-8
Cat. No. CS-0160524
Purity≥98%
MDL No.MFCD23710616

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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6-Bromo-7-methylpyrazolo[1,5-a]pyridine|CS-0160524

Structure of 1427382-24-8

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General Information

CAS No. 1427382-24-8
Cat. No. CS-0160524
Purity ≥98%
MDL No. MFCD23710616
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrN₂
Molecular Weight 211.06
Synonym(s) 6-bromo-7-methyl-pyrazole [1,5-A]pyridine
SMILES CC1=C(Br)C=CC2=CC=NN12

Description

6-Bromo-7-methylpyrazolo[1,5-a]pyridine features a fused heterocyclic core with bromine and methyl substituents at distinct positions, enabling selective functionalization. The electron-deficient pyrazolopyridine scaffold supports efficient cross-coupling reactions under standard conditions, while the steric profile of the 7-methyl group enhances regioselectivity in palladium-catalyzed transformations. This bench-stable compound serves as a key building block for bioactive molecule synthesis.

Application

6-Bromo-7-methylpyrazolo[1,5-a]pyridine serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality. The methyl group at the 7-position enhances regiochemical control and improves solubility in organic media. This compound functions effectively in Suzuki-Miyaura and Stille couplings, facilitating efficient access to substituted pyrazolopyridine scaffolds relevant to medicinal chemistry and materials science.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 17.3
LogP 2.40522
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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6-Bromo-7-methylpyrazolo[1,5-a]pyridine

CAS No. 1427382-24-8

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