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Ethyl 2-((tert-Butoxycarbonyl)amino)-2-(dimethoxyphosphoryl)acetate

  • CAS No. 142602-46-8

  • Cat. No. CS-0042244
  • Molecule weight311.27
  • Purity≥98%
  • MDL No.MFCD02179069

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-((tert-Butoxycarbonyl)amino)-2-(dimethoxyphosphoryl)acetate|CS-0042244

Structure of 142602-46-8

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General Information

  • CAS No. 142602-46-8
  • Cat. No. CS-0042244
  • Purity ≥98%
  • MDL No. MFCD02179069
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂NO₇P
  • Molecular Weight 311.27
  • Synonym(s) Ethyl 2-(Boc-amino)-2-(dimethoxyphosphoryl)acetate
  • SMILES O=C(OCC)C(NC(OC(C)(C)C)=O)P(OC)(OC)=O

Synthesis

  • Route1
    • Ethyl 2-bromo-2-((tert-butoxycarbonyl)amino)acetate|CS-0042243
      85992-86-5
    • null|null
      121-45-9
    • ~%
    • Ethyl 2-((tert-Butoxycarbonyl)amino)-2-(dimethoxyphosphoryl)acetate|CS-0042244
      142602-46-8

    References

    • Vartak, Ashish P.; Skoblenick, Kevin; Thomas, Nancy; Mishra, Ram K.; Johnson, Rodney L. Journal of Medicinal Chemistry, 2007 , vol. 50, # 26 p. 6725 - 6729

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.16
  • LogP   1.8862
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   6

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