tans-4-Hydroxy-D-proline hydrochloride

Name: tans-4-Hydroxy-D-proline hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 142347-81-7
Cat. No. CS-W003511
Purity≥97%
MDL No.MFCD08436165

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tans-4-Hydroxy-D-proline hydrochloride|CS-W003511

Structure of 142347-81-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

trans-4-Hydroxy-D-proline (hydrochloride) is a stereochemically defined proline derivative featuring a hydroxyl group at the C4 position and D-configuration, offering enhanced conformational rigidity. This bench-stable form integrates readily into peptide synthesis workflows, where its constrained ring structure modulates backbone geometry and improves proteolytic resistance in bioactive sequences.

Application

trans-4-Hydroxy-D-proline (hydrochloride) serves as a stereochemically defined building block for the synthesis of peptidomimetics and bioactive heterocycles. Its stable trans configuration and protected hydroxyl group enable reliable incorporation into peptide backbones and facilitate selective derivatization. The hydrochloride salt enhances solubility and handling, supporting efficient coupling reactions and purification in standard synthetic workflows.

General Information

CAS No. 142347-81-7
Cat. No. CS-W003511
Purity ≥97%
MDL No. MFCD08436165
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀ClNO₃
Molecular Weight 167.59
Synonym(s) None
SMILES OC([C@H]1C[C@@H](CN1)O)=O.Cl

Computational Chemistry Data

TPSA 69.56
LogP -0.7844
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Life Science ADC Related Compound Non-cleavable linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

tans-4-Hydroxy-D-proline hydrochloride sigmatans-4-Hydroxy-D-proline hydrochloride manufacturertans-4-Hydroxy-D-proline hydrochloride pricetans-4-Hydroxy-D-proline hydrochloride structuretans-4-Hydroxy-D-proline hydrochloride SDSbuy tans-4-Hydroxy-D-proline hydrochloridetans-4-Hydroxy-D-proline hydrochloride suppliertans-4-Hydroxy-D-proline hydrochloride usestans-4-Hydroxy-D-proline hydrochloride molecular weightprice of tans-4-Hydroxy-D-proline hydrochloridetans-4-Hydroxy-D-proline hydrochloride chemical name formula of tans-4-Hydroxy-D-proline hydrochloride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tans-4-Hydroxy-D-proline hydrochloride

CAS No. 142347-81-7

Recommended Products