Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Amino-5,6-dichloropyrazine-2-carboxamide

  • CAS No. 14229-27-7

  • Cat. No. CS-0099175
  • Purity≥95%
  • MDL No.MFCD21603848

*For research and further manufacturing use only, not for direct human use.

3-Amino-5,6-dichloropyrazine-2-carboxamide|CS-0099175

Structure of 14229-27-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 14229-27-7
  • Cat. No. CS-0099175
  • Purity ≥95%
  • MDL No. MFCD21603848
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Cl₂N₄O
  • Molecular Weight 207.02
  • Synonym(s) None
  • SMILES O=C(N)C1=NC(Cl)=C(N=C1N)Cl

Description

3-Amino-5,6-dichloropyrazine-2-carboxamide features a pyrazine core bearing electron-withdrawing chloro groups and a carboxamide functionality, enabling direct integration into heterocyclic scaffolds. The amino substituent supports further derivatization, while the dichloro pattern enhances reactivity in cross-coupling and nucleophilic substitution processes. This compound serves as a key intermediate in the synthesis of bioactive nitrogen-containing systems.

Application

3-Amino-5,6-dichloropyrazine-2-carboxamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through nucleophilic substitution and coupling reactions. Its dichloro-pyrazine core offers high reactivity for late-stage functionalization, while the amino and carboxamide groups provide orthogonal handles for conjugation. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of kinase inhibitors and other pharmaceutical scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   94.89
  • LogP   0.4645
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 14229-27-7 sigma14229-27-7 manufacturer14229-27-7 price14229-27-7 structure14229-27-7 SDSbuy 14229-27-714229-27-7 supplier14229-27-7 uses14229-27-7 molecular weightprice of 14229-27-714229-27-7 chemical name formula of 14229-27-7
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label