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CS-W001157 4
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4-Phenyltetrahydrofuran-3-ol

  • CAS No. 1420794-90-6

  • Cat. No. CS-0156340
  • Purity≥98%
  • MDL No.MFCD22688533

*For research and further manufacturing use only, not for direct human use.

4-Phenyltetrahydrofuran-3-ol|CS-0156340

Structure of 1420794-90-6

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General Information

  • CAS No. 1420794-90-6
  • Cat. No. CS-0156340
  • Purity ≥98%
  • MDL No. MFCD22688533
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₂
  • Molecular Weight 164.20
  • Synonym(s) Tetrahydro-4-phenyl-3-furanol
  • SMILES C1=CC=C(C=C1)C2COCC2O

Description

4-Phenyltetrahydrofuran-3-ol features a chiral tertiary alcohol flanked by a phenyl ring and a tetrahydrofuran core, offering structural rigidity and enhanced solubility. This scaffold enables direct incorporation into bioactive molecules, particularly in medicinal chemistry applications requiring stereochemical control and metabolic stability.

Application

4-Phenyltetrahydrofuran-3-ol serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard functional group manipulations. Its stable tetrahydrofuran core exhibits favorable bench stability and compatibility with common protecting group strategies. The molecule facilitates stereoselective transformations and functions effectively in coupling reactions, making it valuable for the synthesis of complex scaffolds in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.1613
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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