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CS-W001157 4
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3-Amino-5-hydroxybenzoic acid hydrochloride

  • CAS No. 14206-69-0

  • Cat. No. CS-W002217
  • Purity≥95%
  • MDL No.MFCD00043420

*For research and further manufacturing use only, not for direct human use.

3-Amino-5-hydroxybenzoic acid hydrochloride|CS-W002217

Structure of 14206-69-0

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General Information

  • CAS No. 14206-69-0
  • Cat. No. CS-W002217
  • Purity ≥95%
  • MDL No. MFCD00043420
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClNO₃
  • Molecular Weight 189.60
  • Synonym(s) 3-Carboxy-5-hydroxyanilne hydrochloride, 3-Amino-5-carboxyphenol hydrochloride
  • SMILES O=C(C1=CC(O)=CC(N)=C1)O.Cl

Description

3-Amino-5-hydroxybenzoic acid hydrochloride features a bifunctional aromatic core bearing amino and hydroxyl groups flanking a carboxylic acid, enabling versatile conjugation in medicinal chemistry. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating direct use in peptide coupling, derivatization, and scaffold development for bioactive molecule synthesis.

Application

3-Amino-5-hydroxybenzoic acid hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-dihydroxyamine functionality enables reliable coupling reactions, while the carboxylic acid and protonated amine groups offer complementary handles for derivatization. The hydrochloride salt enhances stability and solubility in aqueous and polar organic media, facilitating purification and handling in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   1.0944
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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