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CS-W001157 4
Total: USD 88.00

N-Hexylamine hydrochloride

  • CAS No. 142-81-4

  • Cat. No. CS-0196786
  • Purity≥98%
  • MDL No.MFCD00043792

*For research and further manufacturing use only, not for direct human use.

N-Hexylamine hydrochloride|CS-0196786

Structure of 142-81-4

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General Information

  • CAS No. 142-81-4
  • Cat. No. CS-0196786
  • Purity ≥98%
  • MDL No. MFCD00043792
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆ClN
  • Molecular Weight 137.65
  • Synonym(s) None
  • SMILES CCCCCCN.Cl

Description

N-Hexylamine hydrochloride offers a long-chain aliphatic amine functionality with enhanced solubility and stability in aqueous systems. This bench-stable salt serves as a versatile scaffold for conjugation chemistry, enabling efficient coupling to biomolecules and functional surfaces. Its hydrophilic counterion facilitates handling under standard laboratory conditions.

Application

N-Hexylamine hydrochloride serves as a versatile amine building block in synthetic organic chemistry, enabling efficient nucleophilic substitution and amine coupling reactions. Its alkyl chain provides favorable solubility and phase separation properties, while the hydrochloride salt enhances bench stability and ease of handling. Widely used in the synthesis of pharmaceutical intermediates, agrochemicals, and functional materials, it functions effectively in amidation, alkylation, and heterocycle formation under standard reaction conditions.

Synthesis

  • Route1
    • null|null
      126424-16-6
    • ~10%
    • In-stock
      N-Hexylamine hydrochloride|CS-0196786
      142-81-4

    References

    • Grieco, Paul A.; Clark, Jerry D. Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2271 - 2272
  • Route2
    • 1-Nitrohexane|CS-0466073
      646-14-0
    • ~96%
    • In-stock
      N-Hexylamine hydrochloride|CS-0196786
      142-81-4

    References

    • Cantillo, David; Moghaddam, Mojtaba Mirhosseini; Kappe, C. Oliver Journal of Organic Chemistry, 2013 , vol. 78, # 9 p. 4530 - 4542
  • Route3
    • null|null
      126681-37-6
    • ~29%
    • In-stock
      N-Hexylamine hydrochloride|CS-0196786
      142-81-4

    References

    • Labeish, N. N.; Porfir'eva, Yu. I.; Petrov, A. A. Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 8.1 p. 1461 - 1467 Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 8 p. 1619 - 1626

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.9472
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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