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(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Dronedarone Impurity

  • CAS No. 141645-16-1

  • Cat. No. CS-0173596
  • Purity≥97%
  • MDL No.MFCD14525622

*For research and further manufacturing use only, not for direct human use.

(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Dronedarone Impurity|CS-0173596

Structure of 141645-16-1

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General Information

  • CAS No. 141645-16-1
  • Cat. No. CS-0173596
  • Purity ≥97%
  • MDL No. MFCD14525622
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₇NO₅
  • Molecular Weight 339.34
  • Synonym(s) methanone, (2-butyl-5-nitro-3-benzofuranyl)(4-hydroxyphenyl)-
  • SMILES O=C(C1=C(CCCC)OC2=CC=C([N+]([O-])=O)C=C12)C3=CC=C(O)C=C3

Synthesis

  • Route1
    • null|null
      100-07-2
    • ~%
    • (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Dronedarone Impurity|CS-0173596
      141645-16-1

    References

    • Journal of the Chinese Chemical Society, , vol. 58, # 7 p. 841 - 845
  • Route2

    References

    • Journal of the Chinese Chemical Society, , vol. 58, # 7 p. 841 - 845
  • Route3
    • 4-Hydroxyacetophenone Paracetamol Impurity|CS-0229792
      99-93-4
    • ~%
    • (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Dronedarone Impurity|CS-0173596
      141645-16-1

    References

    • US2011/178314 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302+H312-H315-H318-H411
Precautionary Statements : P264-P270-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   93.58
  • LogP   4.6202
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   6

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