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Structure of 1416373-06-2
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1-Bromo-3,4,5-trifluoro-2-nitrobenzene features a highly electron-deficient aromatic core stabilized by three fluorine atoms and a nitro group. This trifluorinated scaffold enables efficient coupling reactions under standard conditions, delivering complex fluorinated building blocks for pharmaceutical and agrochemical synthesis.
1-Bromo-3,4,5-trifluoro-2-nitrobenzene serves as a versatile building block in medicinal chemistry and materials synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive aryl bromide functionality. The trifluoromethylated framework enhances metabolic stability and lipophilicity, while the ortho-nitro group provides a handle for selective reduction or further functionalization. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of fluorinated heterocycles and advanced API intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: