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CS-W001157 4
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Methyl 5-hydroxypyrimidine-2-carboxylate

  • CAS No. 1415574-30-9

  • Cat. No. CS-0056562
  • Purity≥95%
  • MDL No.MFCD26521555

*For research and further manufacturing use only, not for direct human use.

Methyl 5-hydroxypyrimidine-2-carboxylate|CS-0056562

Structure of 1415574-30-9

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General Information

  • CAS No. 1415574-30-9
  • Cat. No. CS-0056562
  • Purity ≥95%
  • MDL No. MFCD26521555
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₃
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(C1=NC=C(O)C=N1)OC

Description

Methyl 5-hydroxypyrimidine-2-carboxylate features a pyrimidine core bearing both hydroxyl and ester functionalities, enabling direct integration into heterocyclic synthesis. The hydroxyl group offers a site for derivatization, while the ester facilitates selective transformations under mild conditions. This compound serves as a key intermediate in medicinal chemistry and agrochemical development, combining synthetic versatility with bench-stable handling.

Application

Methyl 5-hydroxypyrimidine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. The hydroxyl group facilitates downstream derivatization via esterification, ether formation, or transition-metal-catalyzed coupling reactions. Its stability under standard bench conditions and compatibility with common protecting group strategies make it ideal for modular synthesis of heterocyclic APIs and functional intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.31
  • LogP   -0.0312
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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