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Structure of 14123-48-9
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This tertiary alcohol features a dimethylamino group that enhances solubility and reactivity in polar media, while the methylated quaternary carbon center imparts steric stability. It functions as a nucleophilic amine surrogate in synthetic transformations, particularly in catalytic systems requiring hindered, moisture-tolerant amines.
1-(Dimethylamino)-2-methylpropan-2-ol serves as a stable, bench-ready tertiary alcohol with enhanced solubility in polar organic solvents. It functions as a versatile building block in synthetic routes requiring sterically hindered alcohols, enabling efficient protection strategies and facilitating nucleophilic substitution reactions. Its dimethylamino group enhances basicity and reactivity in deprotonation or condensation processes, while the tert-butyl-like framework provides structural rigidity and resistance to oxidation. This compound is particularly useful in the synthesis of pharmaceutical intermediates and complex heterocyclic scaffolds due to its predictable reactivity and ease of purification.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H318-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P370+P378-P403+P233-P403+P235-P405-P501
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Lot numbers can be found on the outside label of a product: