5-(Tert-Butyl)-[1,1'-biphenyl]-2-amine

Name: 5-(Tert-Butyl)-[1,1'-biphenyl]-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1410783-24-2
Cat. No. CS-0757408
Molecule weight225.33
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5-(Tert-Butyl)-[1,1'-biphenyl]-2-amine|CS-0757408

Structure of 1410783-24-2

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General Information

CAS No. 1410783-24-2
Cat. No. CS-0757408
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₁₉N
Molecular Weight 225.33
Synonym(s) None
SMILES CC(C)(C)C1=CC=C(N)C(=C1)C1=CC=CC=C1

Description

5-(Tert-Butyl)-[1,1'-biphenyl]-2-amine features a sterically hindered tert-butyl group that enhances solubility and stability in organic media. The biphenyl scaffold provides rigidity and electron-rich character, while the primary amine enables facile derivatization. This compound serves as a robust building block for functionalized ligands and advanced materials.

Application

5-(Tert-Butyl)-[1,1'-biphenyl]-2-amine serves as a versatile building block in synthetic organic chemistry, enabling the construction of functionalized biaryl scaffolds through palladium-catalyzed cross-coupling reactions. The tert-butyl group confers enhanced steric bulk and bench stability, while the primary amine functionality facilitates downstream derivatization. This compound exhibits excellent functional group tolerance and is well-suited for applications in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :	GHS No : GHS07,GHS08
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H351-H412
Precautionary Statements : P264-P270-P273-P280-P330-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 26.02
LogP 4.2333
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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5-(Tert-Butyl)-[1,1'-biphenyl]-2-amine

CAS No. 1410783-24-2

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