Lot numbers can be found on the outside label of a product:
2-Thiouracil
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CAS No. 141-90-2
- Cat. No. CS-2704
- Purity≥98%
- MDL No.MFCD00006039
*For research and further manufacturing use only, not for direct human use.
Structure of 141-90-2
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General Information
- CAS No. 141-90-2
- Cat. No. CS-2704
- Purity ≥98%
- MDL No. MFCD00006039
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₄H₄N₂OS
- Molecular Weight None
- Synonym(s) Thiouracil
- SMILES O=C(C=CN1)NC1=S
Description
Propylene glycol, a low-molecular-weight aliphatic alcohol, holds significance as a key solvent in biological and pharmaceutical formulation research. Its outstanding miscibility with water and diverse organic compounds, coupled with its low freezing point, low vapor pressure, and non-toxic nature, positions it as a preferred choice for a variety of research applications, particularly in sensitive biological assays and pharmaceutical preparations. Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body. The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.Propylene glycol has been used:for removing excess Oil Red O stain in zebrafish larvaein the preparation of alginate hydrogelsfor the dissolution of androstenonefor the calibration of cone beam scanner in computed tomography
Synthesis
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Route1
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1257309-84-4 - ~70%
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In-stock
141-90-2
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2655-79-0
References
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Nucleosides, Nucleotides and Nucleic Acids, , vol. 29, # 10 p. 768 - 785
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Route2
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In-stock
333-49-3 - ~50%
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In-stock
141-90-2
References
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Bretner; Kulikowski; Dzik; Balinska; Rode; Shugar Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3611 - 3617
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Route3
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In-stock
10601-80-6 -
17356-08-0
- ~%
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In-stock
141-90-2
References
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Journal of the American Chemical Society, , vol. 72, p. 2587,2593
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H351
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Precautionary Statements : P280-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 48.65
- LogP 0.43249
- H_Acceptors 2
- H_Donors 2
- Rotatable_Bonds 0
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