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CS-W001157 4
Total: USD 88.00

(DHQ)2PHAL

  • CAS No. 140924-50-1

  • Cat. No. CS-W002502
  • Purity≥98%
  • MDL No.MFCD28014549

*For research and further manufacturing use only, not for direct human use.

(DHQ)2PHAL|CS-W002502

Structure of 140924-50-1

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General Information

  • CAS No. 140924-50-1
  • Cat. No. CS-W002502
  • Purity ≥98%
  • MDL No. MFCD28014549
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₈H₅₄N₆O₄
  • Molecular Weight 778.98
  • Synonym(s) Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine
  • SMILES CC[C@@H]1[C@@]2([H])CC[N@@](C1)[C@](C2)([H])[C@H](OC3=NN=C(C4=C3C=CC=C4)O[C@@H]([C@]5([H])C[C@]6([H])CC[N@]5C[C@@H]6CC)C7=CC=NC8=C7C=C(OC)C=C8)C9=C(C=C(OC)C=C%10)C%10=NC=C9

Description

DHQ)2PHAL is a modified cinchona alkaloid.(DHQ)2PHAL may be used in the following processes:As a catalyst Asymmetric and chemoselective N-allylic alkylation of indoles with Morita-Baylis-Hillman carbonates to form pyrrolo[1,2-a]indole and pyrrolo[3,2,1-ij]quinoline derivatives.As a ligand for the osmium catalyzed-Sharpless asymmetric dihydroxylation step of (S)-a-benzoyloxy carboxylic acids multistep synthesis.As a ligand for the carbamate based asymmetric aminohydroxylation of styrene derivatives to form N-carbamate protected R-arylglycinols.

Synthesis

  • Route1

    References

    • Journal of Organic Chemistry, , vol. 57, # 10 p. 2768 - 2771

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

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Computational Chemistry Data

  • TPSA   94.96
  • LogP   9.2244
  • H_Acceptors   10
  • H_Donors   0
  • Rotatable_Bonds   12

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