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CS-W001157 4
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2-(3-(Aminomethyl)phenoxy)-n,n-dimethylethanamine

  • CAS No. 140836-70-0

  • Cat. No. CS-0249424
  • Molecule weight194.27
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(3-(Aminomethyl)phenoxy)-n,n-dimethylethanamine|CS-0249424

Structure of 140836-70-0

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General Information

  • CAS No. 140836-70-0
  • Cat. No. CS-0249424
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₈N₂O
  • Molecular Weight 194.27
  • Synonym(s) [2-(3-Aminomethyl-phenoxy)-ethyl]-dimethyl-amine
  • SMILES CN(C)CCOC1=CC=CC(=C1)CN

Synthesis

  • Route1
    • 3-(2-(Dimethylamino)ethoxy)benzonitrile|CS-0965709
      500024-50-0
    • ~61%
    • 2-(3-(Aminomethyl)phenoxy)-n,n-dimethylethanamine|CS-0249424
      140836-70-0

    References

    • SENTINEL ONCOLOGY LIMITED; BOYLE, Robert, George; WALKER, David, Winter Patent: WO2010/136755 A1, 2010 ; Location in patent: Page/Page column 58 ; WO 2010/136755 A1
  • Route2
    • null|null
      140836-71-1
    • ~%
    • 2-(3-(Aminomethyl)phenoxy)-n,n-dimethylethanamine|CS-0249424
      140836-70-0

    References

    • Sakaguchi; Nishino; Ogawa; Iwanaga; Yasuda; Kato; Ito Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 1 p. 202 - 211
  • Route3
    • null|null
      1242928-95-5
    • ~21%
    • 2-(3-(Aminomethyl)phenoxy)-n,n-dimethylethanamine|CS-0249424
      140836-70-0

    References

    • Nhu, Duong; Duffy, Sandra; Avery, Vicky M.; Hughes, Andrew; Baell, Jonathan B. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4496 - 4498

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H315-H318-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.49
  • LogP   1.0857
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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