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CS-W001157 4
Total: USD 88.00

2-(4-Iodo-1H-pyrazol-1-yl)ethanol

  • CAS No. 1408334-75-7

  • Cat. No. CS-0041660
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-Iodo-1H-pyrazol-1-yl)ethanol|CS-0041660

Structure of 1408334-75-7

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General Information

  • CAS No. 1408334-75-7
  • Cat. No. CS-0041660
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇IN₂O
  • Molecular Weight 238.03
  • Synonym(s) 4-Iodo-1H-pyrazole-1-ethanol
  • SMILES IC1=CN(CCO)N=C1

Description

2-(4-Iodo-1H-pyrazol-1-yl)ethanol features a reactive iodo substituent on a pyrazole core, enabling efficient coupling in cross-coupling transformations. The pendant ethanol group provides solubility and handles well under standard conditions. This scaffold integrates readily into bioactive molecules and functional materials.

Application

2-(4-Iodo-1H-pyrazol-1-yl)ethanol serves as a versatile building block for Suzuki-Miyaura and Buchwald-Hartwig coupling reactions, enabling efficient construction of biaryl and aryl-ether scaffolds. The iodide functionality offers high reactivity under palladium catalysis, while the pendant ethanol group provides a handle for further derivatization or purification via chromatography. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.48
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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