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Potassium (2-benzyloxyethyl)trifluoroborate

  • CAS No. 1408168-73-9

  • Cat. No. CS-0211554
  • Molecule weight242.09
  • Purity≥97%
  • MDL No.MFCD22684708

*For research and further manufacturing use only, not for direct human use.

Potassium (2-benzyloxyethyl)trifluoroborate|CS-0211554

Structure of 1408168-73-9

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General Information

  • CAS No. 1408168-73-9
  • Cat. No. CS-0211554
  • Purity ≥97%
  • MDL No. MFCD22684708
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BF₃KO
  • Molecular Weight 242.09
  • Synonym(s) None
  • SMILES [F-][B+3]([F-])([CH2-]COCC1=CC=CC=C1)[F-].[K+]

Description

Potassium (2-benzyloxyethyl)trifluoroborate delivers a stable, bench-ready boron source for Suzuki-Miyaura cross-coupling reactions. The benzyloxyethyl group enhances solubility and functional group tolerance, enabling efficient C–C bond formation under mild conditions. This reagent integrates seamlessly into synthetic workflows requiring precise boron delivery without protodeboronation.

Application

Potassium (2-benzyloxyethyl)trifluoroborate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoroborate group enables efficient C–C bond formation under mild conditions, with the benzyloxyethyl protecting group offering orthogonal stability and convenient deprotection. This reagent facilitates the synthesis of functionalized alkylated arenes and heterocyclic scaffolds commonly encountered in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   0.0546
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

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