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Structure of 1408057-44-2
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(S)-(4,4-Difluoro-1-methylpyrrolidin-2-yl)methanol is a chiral building block featuring a sterically constrained pyrrolidine core with dual fluorine atoms at the C4 position. The methanol functionality enables direct derivatization, while the (S)-configuration ensures high stereocontrol in asymmetric synthesis. This bench-stable, moisture-tolerant reagent integrates efficiently into complex molecular architectures.
(S)-(4,4-Difluoro-1-methylpyrrolidin-2-yl)methanol serves as a valuable chiral building block in medicinal chemistry, enabling efficient access to fluorinated pyrrolidine scaffolds prevalent in bioactive molecules. Its bench-stable nature and compatibility with standard coupling and functionalization protocols facilitate streamlined synthesis of drug candidates. The difluoro substitution enhances metabolic stability, while the hydroxymethyl group provides a versatile handle for further derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: