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CS-W001157 4
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(2-aminobenzo[d]oxazol-5-yl)boronic acid hydrochloride

  • CAS No. 1404480-15-4

  • Cat. No. CS-0173771
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-aminobenzo[d]oxazol-5-yl)boronic acid hydrochloride|CS-0173771

Structure of 1404480-15-4

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General Information

  • CAS No. 1404480-15-4
  • Cat. No. CS-0173771
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BClN₂O₃
  • Molecular Weight 214.41
  • Synonym(s) (2-Aminobenzo[d]oxazol-5-yl)-boronic acid hydrochloride
  • SMILES Cl.OB(O)C=1C=CC=2OC(=NC2C1)N

Description

This bench-stable boronic acid derivative features a fused oxazole ring system, enhancing electronic stability and facilitating efficient cross-coupling reactions. The hydrochloride salt improves solubility in aqueous and polar organic media, enabling seamless integration into synthetic workflows requiring precise functional group tolerance and reliable reactivity.

Application

(2-aminobenzo[d]oxazol-5-yl)boronic acid hydrochloride serves as a stable, bench-ready building block for Suzuki-Miyaura coupling reactions. Its ortho-amino and oxazole functionalities enable efficient construction of biologically relevant heterocyclic scaffolds. The hydrochloride salt enhances solubility and handling, while the boronic acid group exhibits robust compatibility with diverse coupling partners, facilitating rapid access to complex molecular architectures in medicinal chemistry and materials synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   92.51
  • LogP   -0.4884
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   1

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