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Structure of 1403766-94-8
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Methyl 3-azabicyclo[3.2.1]octane-8-carboxylate hydrochloride features a rigid, nitrogen-containing bicyclic scaffold with a bench-stable protonated amine and a polar ester handle. This configuration enables efficient incorporation into diverse synthetic pathways, particularly in medicinal chemistry campaigns requiring constrained, bioactive heterocyclic cores.
Methyl 3-azabicyclo[3.2.1]octane-8-carboxylate hydrochloride serves as a conformationally constrained bicyclic scaffold for medicinal chemistry and asymmetric synthesis. The tertiary amine functionality enables efficient salt formation, enhancing solubility and crystallinity. It participates reliably in nucleophilic substitution and reductive amination reactions, facilitating access to diverse heterocyclic architectures. The methyl ester group supports standard transformations including hydrolysis, amidation, and coupling protocols, making it a versatile building block for API development and library synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: