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Structure of 1402664-68-9
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4-Chloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one is a bench-stable heterocyclic scaffold featuring a chlorinated pyrrolidine core fused to a pyridinone ring. This electron-deficient system integrates readily into medicinal chemistry campaigns, serving as a key building block for kinase inhibitors and bioactive small molecules. The chlorine substituent enhances metabolic stability and enables downstream functionalization via cross-coupling reactions.
4-Chloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its electrophilic chlorine at the C4 position enables facile Suzuki-Miyaura, Buchwald-Hartwig, and nucleophilic substitution reactions. The dihydro-pyrrolopyridinone core provides structural rigidity and hydrogen-bonding capacity, enhancing target affinity in kinase inhibitors and CNS-active compounds. Bench-stable and readily purified by column chromatography, it functions efficiently in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: