(R)-2-Amino-2-cyclopropylethanol hydrochloride

Name: (R)-2-Amino-2-cyclopropylethanol hydrochloride
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CAS No. 1401163-31-2
Cat. No. CS-0111762
Purity≥97%
MDL No.MFCD28975219

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(R)-2-Amino-2-cyclopropylethanol hydrochloride|CS-0111762

Structure of 1401163-31-2

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General Information

CAS No. 1401163-31-2
Cat. No. CS-0111762
Purity ≥97%
MDL No. MFCD28975219
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂ClNO
Molecular Weight 137.61
Synonym(s) (2R)-2-AMINO-2-CYCLOPROPYLETHAN-1-OL HYDROCHLORIDE
SMILES OC[C@H](N)C1CC1.[H]Cl

Description

(R)-2-Amino-2-cyclopropylethanol hydrochloride is a chiral building block featuring a sterically constrained cyclopropyl group adjacent to a primary amine. This configuration imparts enhanced stability and defined stereochemistry, enabling precise incorporation into bioactive molecules. The hydrochloride salt ensures excellent solubility and handling under standard bench conditions.

Application

(R)-2-Amino-2-cyclopropylethanol hydrochloride serves as a chiral building block for medicinal chemistry applications, offering a rigid cyclopropyl moiety adjacent to a primary amine. Its stability under standard synthetic conditions and compatibility with common coupling reactions facilitate efficient incorporation into bioactive scaffolds. The hydrochloride salt enhances solubility and handling, enabling straightforward purification and use in peptide-like sequences or heterocycle synthesis.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

TPSA 46.25
LogP 0.1378
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-Amino-2-cyclopropylethanol hydrochloride

CAS No. 1401163-31-2

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