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(R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile

  • CAS No. 1401031-38-6

  • Cat. No. CS-0084596
  • Purity≥98%
  • MDL No.MFCD28134617

*For research and further manufacturing use only, not for direct human use.

(R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile|CS-0084596

Structure of 1401031-38-6

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General Information

  • CAS No. 1401031-38-6
  • Cat. No. CS-0084596
  • Purity ≥98%
  • MDL No. MFCD28134617
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₀N₂O
  • Molecular Weight 256.35
  • Synonym(s) None
  • SMILES N#CC[C@@](C1)(C2=NC=CC=C2)CCOC31CCCC3

Description

(R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile features a rigid spirocyclic scaffold with a pyridinyl substituent and nitrile functionality, offering enhanced metabolic stability and defined stereochemistry for targeted applications in medicinal chemistry.

Application

(R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile serves as a versatile chiral building block for the synthesis of spirocyclic heterocycles and bioactive scaffolds. The nitrile group enables downstream transformations such as amide formation or hydrolysis, while the pyridinyl moiety provides a handle for metal coordination and further functionalization. Its rigid spirocyclic framework offers defined stereochemistry and conformational stability, facilitating efficient access to complex architectures in medicinal chemistry and catalysis applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.91
  • LogP   3.35628
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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