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CS-W001157 4
Total: USD 88.00

3-(Methylsulfonyl)azetidine hydrochloride

  • CAS No. 1400764-60-4

  • Cat. No. CS-W021777
  • Molecule weight171.65
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Methylsulfonyl)azetidine hydrochloride|CS-W021777

Structure of 1400764-60-4

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General Information

  • CAS No. 1400764-60-4
  • Cat. No. CS-W021777
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO₂S
  • Molecular Weight 171.65
  • Synonym(s) 3-Methylsulfonyl-azetidine hydrochloride
  • SMILES O=S(C1CNC1)(C)=O.[H]Cl

Description

3-(Methylsulfonyl)azetidine hydrochloride delivers a rigid, electron-deficient azetidine core ideal for probing bioisosteric effects in medicinal chemistry. The methylsulfonyl group enhances solubility and metabolic stability while the hydrochloride salt ensures improved handling and crystallinity under standard conditions.

Application

3-(Methylsulfonyl)azetidine hydrochloride serves as a stable, bench-ready building block for medicinal chemistry, enabling efficient incorporation of the methylsulfonyl group into azetidine scaffolds. Its high functional group tolerance and compatibility with standard coupling protocols facilitate rapid diversification in target-oriented synthesis. The hydrochloride salt enhances solubility and crystallinity, simplifying purification and handling in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.17
  • LogP   -0.5754
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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