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Structure of 14005-14-2
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2,2-Dimethylbenzo[d][1,3]dioxole features a rigid, electron-rich benzodioxole core with steric protection from the dimethyl substitution at the bridgehead position. This configuration enhances stability and modulates electronic properties, making it valuable in medicinal chemistry and materials synthesis.
2,2-Dimethylbenzo[d][1,3]dioxole serves as a stable, bench-ready heterocyclic building block featuring a rigid fused ring system with excellent functional group tolerance. Its dimethyl substitution enhances solubility and metabolic stability while preserving reactivity in palladium-catalyzed cross-coupling processes. The structure functions effectively as a bioisostere for phenyl or pyridine moieties in medicinal chemistry and enables efficient incorporation into complex scaffolds via standard electrophilic functionalization or Suzuki-Miyaura coupling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: