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Structure of 1392213-15-8
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(1-Aminocyclobutyl)methanol hydrochloride features a strained cyclobutyl ring fused to a primary amine and hydroxymethyl group, delivering high reactivity in nucleophilic transformations. The protonated amine enhances solubility in aqueous systems while maintaining stability under standard bench conditions. This scaffold serves as a key building block for bioactive molecule synthesis, particularly in peptidomimetic and conformationally restricted compound libraries.
(1-Aminocyclobutyl)methanol hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of cyclobutane-containing scaffolds prevalent in bioactive molecules. Its amine functionality facilitates straightforward derivatization via alkylation, acylation, or reductive amination, while the hydrochloride salt ensures excellent bench stability and ease of handling. The molecule’s constrained cyclobutyl ring imparts conformational rigidity, enhancing target binding affinity in drug discovery applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: