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CS-W001157 4
Total: USD 88.00

7-Azaspiro[3.5]nonan-2-one hydrochloride

  • CAS No. 1392211-51-6

  • Cat. No. CS-0043724
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Azaspiro[3.5]nonan-2-one hydrochloride|CS-0043724

Structure of 1392211-51-6

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General Information

  • CAS No. 1392211-51-6
  • Cat. No. CS-0043724
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄ClNO
  • Molecular Weight 175.66
  • Synonym(s) None
  • SMILES O=C1CC2(CCNCC2)C1.[H]Cl

Description

7-Azaspiro[3.5]nonan-2-one hydrochloride features a rigid spirocyclic core with a nitrogen atom at the 7-position, delivering enhanced stability and defined stereochemistry. This bench-stable, moisture-tolerant heterocycle serves as a key scaffold in medicinal chemistry for constructing bioactive molecules with improved solubility and metabolic resilience.

Application

7-Azaspiro[3.5]nonan-2-one hydrochloride serves as a versatile scaffold for medicinal chemistry campaigns, offering a rigid, bicyclic structure with a ketone and secondary amine functionality. The hydrochloride salt enhances solubility and stability, facilitating purification and handling in synthetic workflows. It enables efficient access to nitrogen-containing heterocycles via reductive amination or nucleophilic addition, supporting applications in target-oriented synthesis and fragment-based drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.1409
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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