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(S)-2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid

  • CAS No. 138514-97-3

  • Cat. No. CS-0063819
  • Purity≥95%
  • MDL No.MFCD09264337
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid|CS-0063819

Structure of 138514-97-3

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Description

(S)-2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid features a chiral center at the α-carbon, delivering enantiomerically pure access to bioactive indole-containing peptides. The electron-deficient 7-fluoro substitution enhances metabolic stability and modulates receptor affinity. This amino acid integrates readily into peptide sequences under standard coupling conditions, offering a handle for targeted drug discovery applications in CNS and oncology research.

Application

(S)-2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid serves as a key chiral building block for the synthesis of biologically active indole-containing compounds. Its well-defined stereochemistry and functional group compatibility facilitate incorporation into peptide analogs and heterocyclic scaffolds. The molecule exhibits good bench stability and enables efficient coupling reactions, making it valuable for medicinal chemistry campaigns targeting CNS and oncology therapeutics.

General Information

  • CAS No. 138514-97-3
  • Cat. No. CS-0063819
  • Purity ≥95%
  • MDL No. MFCD09264337
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁FN₂O₂
  • Molecular Weight 222.22
  • Synonym(s) H-Trp(7-F)-OH
  • SMILES N[C@@H](CC1=CNC2=C(F)C=CC=C12)C(O)=O

Computational Chemistry Data

  • TPSA   79.11
  • LogP   1.2614
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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