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Structure of 1384870-47-6
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DBCO-NHS ester 2 delivers efficient bioconjugation under physiological conditions, combining the strain-promoted cycloaddition of DBCO with the reactive NHS ester for rapid, site-specific labeling. This bench-stable reagent enables seamless coupling to primary amines on proteins and biomolecules, streamlining probe integration in chemical biology workflows.
DBCO-NHS ester 2 is a bioorthogonal reagent that enables efficient, selective conjugation of primary amines under physiological conditions. It functions as a stable, water-tolerant coupling agent with high reactivity toward amine-containing biomolecules, facilitating site-specific labeling and probe immobilization. The cyclooctyne moiety enables rapid strain-promoted azide-alkyne cycloaddition (SPAAC), while the NHS ester provides reliable activation for amine functionalization. Ideal for protein modification, antibody-drug conjugate synthesis, and surface functionalization in complex biological matrices.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: