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CS-W001157 4
Total: USD 88.00

7-Chloroimidazo[1,2-b]pyridazine

  • CAS No. 1383481-11-5

  • Cat. No. CS-W006906
  • Purity≥98%
  • MDL No.MFCD24387377

*For research and further manufacturing use only, not for direct human use.

7-Chloroimidazo[1,2-b]pyridazine|CS-W006906

Structure of 1383481-11-5

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General Information

  • CAS No. 1383481-11-5
  • Cat. No. CS-W006906
  • Purity ≥98%
  • MDL No. MFCD24387377
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClN₃
  • Molecular Weight 153.57
  • Synonym(s) None
  • SMILES ClC1=CC2=NC=CN2N=C1

Description

7-Chloroimidazo[1,2-b]pyridazine is a heterocyclic compound featuring a chlorinated imidazopyridazine core. This electron-deficient scaffold integrates readily into medicinal chemistry campaigns, serving as a key building block for kinase inhibitors and CNS-targeted therapeutics. The chlorine substituent enhances metabolic stability and facilitates downstream functionalization via palladium-catalyzed cross-coupling reactions.

Application

7-Chloroimidazo[1,2-b]pyridazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to imidazopyridazine scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. The chlorine substituent facilitates nucleophilic substitution reactions, supporting late-stage functionalization. Its stability under standard synthetic conditions and compatibility with common coupling protocols make it a practical choice for modular library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   1.3827
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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