N,N'-Bis-Boc-D-ornithine

Name: N,N'-Bis-Boc-D-ornithine
Brand: ChemScene
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CAS No. 137524-82-4
Cat. No. CS-0372492
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 137524-82-4
Cat. No. CS-0372492
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₈N₂O₆
Molecular Weight 332.39
Synonym(s) Boc-D-orn(boc)-OH
SMILES CC(C)(C)OC(N[C@@H](C(O)=O)CCCNC(OC(C)(C)C)=O)=O

Description

N,N'-Bis-Boc-D-ornithine features two Boc-protected amine groups on the D-ornithine backbone, enabling stable incorporation into peptide chains. This derivative delivers enhanced solubility and reduced side reactivity during synthetic workflows, simplifying purification and improving yield in solid-phase peptide synthesis.

Application

N,N'-Bis-Boc-D-ornithine serves as a robust, bench-stable building block for the synthesis of D-ornithine-containing peptides and heterocyclic scaffolds. Its dual Boc protection enables selective deprotection and orthogonal functionalization in solid-phase and solution-phase peptide coupling workflows. The molecule exhibits excellent solubility in common organic solvents and tolerates a wide range of reaction conditions, facilitating efficient incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

TPSA 113.96
LogP 2.2692
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 6

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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N,N'-Bis-Boc-D-ornithine

CAS No. 137524-82-4

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