Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl ((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methyl)carbamate

  • CAS No. 1374451-83-8

  • Cat. No. CS-0368503
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD26516727

*For research and further manufacturing use only, not for direct human use.

tert-Butyl ((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methyl)carbamate|CS-0368503

Structure of 1374451-83-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1374451-83-8
  • Cat. No. CS-0368503
  • Purity ≥97%
  • MDL No. MFCD26516727
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₇BN₂O₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCC1=NC=C(B2OC(C)(C)C(C)(C)O2)C=C1

Description

tert-Butyl ((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methyl)carbamate features a boronate handle integrated into a pyridine scaffold, enabling efficient Suzuki-Miyaura coupling. The tert-butyl carbamate group provides stability and convenient deprotection, while the tetramethyl-dioxaborolane moiety ensures high functional group tolerance and reactivity under mild conditions. This compound serves as a robust building block for constructing complex heteroaromatic architectures in medicinal chemistry and materials science.

Application

tert-Butyl ((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methyl)carbamate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyridylmethyl scaffold enables efficient functionalization at the 5-position, while the Bpin group offers excellent stability, mild handling requirements, and compatibility with diverse reaction conditions. Its tert-butyl carbamate protecting group ensures orthogonality and ease of removal under standard acidic conditions, facilitating downstream derivatization in medicinal chemistry and materials synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   69.68
  • LogP   2.4055
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1374451-83-8 sigma1374451-83-8 manufacturer1374451-83-8 price1374451-83-8 structure1374451-83-8 SDSbuy 1374451-83-81374451-83-8 supplier1374451-83-8 uses1374451-83-8 molecular weightprice of 1374451-83-81374451-83-8 chemical name formula of 1374451-83-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label