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Structure of 137419-24-0
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tert-Butyl spiro[indene-1,4'-piperidine]-1'-carboxylate delivers a rigid, three-dimensional scaffold ideal for medicinal chemistry applications. The spirocyclic indene-piperidine core combines steric bulk with defined spatial orientation, enabling precise control over molecular conformation. This bench-stable derivative supports efficient incorporation into complex target molecules under standard coupling conditions.
tert-Butyl spiro[indene-1,4'-piperidine]-1'-carboxylate serves as a versatile scaffold for the construction of complex polycyclic frameworks, enabling efficient access to bioactive indole and piperidine-based architectures. Its spirocyclic core offers rigidity and defined stereochemistry, while the tert-butyl carbamate group provides bench stability and facile deprotection under mild acidic conditions. The molecule functions as a key building block in medicinal chemistry campaigns targeting CNS-directed therapeutics and kinase inhibitors, with broad compatibility in standard coupling and cyclization reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P261-P280-P304+P340
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Lot numbers can be found on the outside label of a product: