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Structure of 137401-45-7
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This malonate derivative features a tert-butoxycarbonyl-protected amine and an ethoxy-substituted β-keto ester moiety, enabling direct incorporation into peptide synthesis workflows. The electrophilic β-carbon facilitates nucleophilic addition reactions under mild conditions, while the bench-stable protecting group simplifies purification and handling in multi-step sequences.
2-((tert-Butoxycarbonyl)amino)-3-ethoxy-3-oxopropanoic acid serves as a versatile synthon in peptide and heterocyclic synthesis, enabling efficient access to β-amino carbonyl scaffolds. The protected amine and ester-functionalized β-keto acid moiety facilitate sequential transformations including cyclizations, nucleophilic additions, and decarboxylation reactions. Its bench-stable nature and compatibility with standard purification methods make it suitable for multi-step synthetic sequences in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: