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Structure of 1372197-49-3
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6-(Trifluoromethyl)imidazo[1,2-a]pyrazine-2-carboxylic acid features a fused heterocyclic core bearing a trifluoromethyl group at the 6-position and a carboxylic acid functionality at the 2-position. This combination imparts enhanced electron-withdrawing character and improved solubility in polar solvents, enabling efficient integration into bioactive scaffolds for medicinal chemistry applications under standard bench conditions.
6-(Trifluoromethyl)imidazo[1,2-a]pyrazine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry campaigns, enabling the construction of bioactive scaffolds through standard amide coupling and derivatization protocols. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid functionality facilitates direct conjugation or salt formation. Bench-stable and compatible with common synthetic workflows, it functions effectively in both solution-phase and solid-phase synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: