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Structure of 137-45-1
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1H-pyrazol-3(2H)-one features a core heterocyclic scaffold with tautomeric equilibrium between lactam and enol forms, enabling versatile participation in transition-metal-catalyzed couplings and cycloadditions. This bench-stable, moisture-tolerant compound integrates readily into medicinal chemistry libraries as a privileged scaffold for kinase inhibitors and antiviral agents.
1H-Pyrazol-3(2H)-one serves as a versatile scaffold for constructing biologically relevant heterocycles and functionalized building blocks. Its tautomeric equilibrium enables diverse reactivity, facilitating nucleophilic additions, electrophilic substitutions, and transition-metal-catalyzed couplings. The compound exhibits bench stability, ease of purification, and compatibility with common protecting group strategies, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: