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CS-W001157 4
Total: USD 88.00

2-Isopropylpyridin-3-amine

  • CAS No. 1369105-90-7

  • Cat. No. CS-0154299
  • Purity≥98%
  • MDL No.MFCD22071262

*For research and further manufacturing use only, not for direct human use.

2-Isopropylpyridin-3-amine|CS-0154299

Structure of 1369105-90-7

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General Information

  • CAS No. 1369105-90-7
  • Cat. No. CS-0154299
  • Purity ≥98%
  • MDL No. MFCD22071262
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight 136.19
  • Synonym(s) 2-Isopropyl-3-pyridinamine
  • SMILES CC(C)C1=C(C=CC=N1)N

Description

2-Isopropylpyridin-3-amine features a pyridine core with a para-substituted isopropylamino group, delivering enhanced solubility and steric bulk. This configuration enables efficient coordination in transition metal catalysis and improves stability under ambient conditions. The molecule integrates readily into ligand architectures for cross-coupling applications.

Application

2-Isopropylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and direct functionalization. Its pyridine core provides strong coordination for transition metals, while the isopropyl and primary amine groups offer orthogonal reactivity and enhanced solubility. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.7872
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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