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CS-W001157 4
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5-Bromo-2-(5-bromothiophen-2-yl)pyridine

  • CAS No. 136902-53-9

  • Cat. No. CS-0181802
  • Purity≥98%
  • MDL No.MFCD29765747

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-(5-bromothiophen-2-yl)pyridine|CS-0181802

Structure of 136902-53-9

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General Information

  • CAS No. 136902-53-9
  • Cat. No. CS-0181802
  • Purity ≥98%
  • MDL No. MFCD29765747
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅Br₂NS
  • Molecular Weight 319.02
  • Synonym(s) 5-Bromo-2-(5-bromo-2-thienyl)pyridine
  • SMILES BrC1=CC=C(C2=NC=C(Br)C=C2)S1

Description

5-Bromo-2-(5-bromothiophen-2-yl)pyridine features a pyridine core fused with a brominated thiophene unit, delivering enhanced electronic modulation and structural rigidity. This dual-halogenated scaffold enables efficient cross-coupling reactions under standard conditions, serving as a robust building block for advanced heterocyclic architectures in materials science and pharmaceutical development.

Application

5-Bromo-2-(5-bromothiophen-2-yl)pyridine serves as a versatile building block for constructing biheterocyclic scaffolds in medicinal chemistry and materials science. The molecule enables palladium-catalyzed cross-coupling reactions due to its dual bromo substituents, offering high functional group tolerance and compatibility with standard Suzuki, Stille, and Negishi protocols. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis of complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   4.3351
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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