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CS-W001157 4
Total: USD 88.00

2-(Cyclopent-2-en-1-yl)acetic acid

  • CAS No. 13668-61-6

  • Cat. No. CS-0147114
  • Purity≥95%
  • MDL No.MFCD00001400

*For research and further manufacturing use only, not for direct human use.

2-(Cyclopent-2-en-1-yl)acetic acid|CS-0147114

Structure of 13668-61-6

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General Information

  • CAS No. 13668-61-6
  • Cat. No. CS-0147114
  • Purity ≥95%
  • MDL No. MFCD00001400
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₂
  • Molecular Weight 126.15
  • Synonym(s) cyclopent-2-en-1-ylacetic acid
  • SMILES O=C(O)CC1C=CCC1

Description

This cyclopentenylacetic acid derivative features a conjugated cyclopentenyl ring fused to a pendant acetic acid group, enabling facile integration into bioactive scaffolds. The rigid, electron-rich framework supports stereoselective transformations and serves as a key building block in natural product synthesis and medicinal chemistry campaigns.

Application

2-(Cyclopent-2-en-1-yl)acetic acid serves as a versatile building block for cyclopentenyl-containing scaffolds, enabling efficient access to bioactive molecules through established functional group transformations. Its conjugated enone-like system supports electrophilic and nucleophilic reactions, while the carboxylic acid facilitates direct coupling or derivatization. The compound exhibits good bench stability and is compatible with standard purification protocols, making it suitable for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      134682-20-5
    • ~60%
    • In-stock
      2-(Cyclopent-2-en-1-yl)acetic acid|CS-0147114
      13668-61-6

    References

    • Hwu, Jih Ru; Shiao, Shui-Sheng; Tsay, Shwu-Chen Journal of the American Chemical Society, 2000 , vol. 122, # 24 p. 5899 - 5900
  • Route2
    • null|null
      88444-66-0
    • ~59%
    • In-stock
      2-(Cyclopent-2-en-1-yl)acetic acid|CS-0147114
      13668-61-6

    References

    • Trend, Raissa M.; Ramtohul, Yeeman K.; Stoltz, Brian M. Journal of the American Chemical Society, 2005 , vol. 127, # 50 p. 17778 - 17788
  • Route3
    • null|null
      142-29-0
    • ~%
    • In-stock
      2-(Cyclopent-2-en-1-yl)acetic acid|CS-0147114
      13668-61-6

    References

    • Journal of the American Chemical Society, , vol. 127, # 50 p. 17778 - 17788

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.4273
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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